This sumo wrestler is not as strong as he seems. Sure he has high health being at 500,000, but his attack power is rather low, not even reaching 6,000. His standing range is also something to be considered, being at a measly 100, however, take note of his Omni Strike range as it is able to reach up to 300 meaning that he is able to outrange many close ranged attackers. He also has a 100% chance to knockback all Cat Units.
Units such as Macho Leg Cat, King Dragon Cat, the crazedcounterparts, Cyborg Cat and more can hit E. Honda from a safe distance. Anything that is Immune to knockback, especially tankers, should be avoided, as this doesn't allow them to be pushed from a safe range away from E. Honda and will be continuously hit by his attacks. Any unit that can do damage in a singular blow is more effective, as that will trigger less of his knockbacks, and thus less of his attacks.