Homulilly is an incredibly tough enemy, with 9 million health, exceptional range, Base Destroyer and immunity to most effects. Because of her Omni Strike, she only needs to get within 1800 range of the Cat Base to damage it and, with Base Destroyer, she deals 48,000 damage per hit. The worst thing she has going for her is her weaken ability, which for any cat not immune to weaken effectively doubles her health to 18 million. The best way to defeat her is with Li'l Madoka's and Li'l Homura's Combo, My Very Best Friend, combined with Uber Rares from the collab. If such Ubers are not available, others like Balrog Cat can also be very effective.