One of the most powerful Alien peons, Mesocosmocyclone is essentially a much frailer but much faster version of Super Cosmic Cyclone that warps cats forward instead of backward. Despite its high stats and attack rate, Mesocosmocyclone's range is only 50, meaning everything can outrange it.
DO NOT UNDERESTIMATE THIS ENEMY! Remember, this enemy, while small, is still a Cyclone, so its DPS is off the charts. You will want to kill this thing as fast as possible before it shreds through your frontlines. Elemental Pixieubers are ideal for dealing with it, provided they are decently leveled.
Rover Cat will help a lot when fighting this enemy, but he will still only last a couple of seconds. Iron Wall Cat can halt his movement for a few seconds, when at high levels.
Corrupted Psychocat is also a very good and consistent option as a crowd controller, as he can impede Mesocosmocyclone's advance so your other attackers can burst it down. Seafarer Cat can do the same, but it is recommended you invest in his Talents, which will improve Seafarer's reliability.