Mr. Puffington combines some of the qualities found in Brollow and Rain D. and deals much higher damage than all other Relic enemies seen at this point in the game. His attack has an Omni Strike that inflicts curse for 10 seconds, paralleling the time his attack animation takes to start again.
Do not use units with low damage per hit because they will constantly knock him back, allowing him to attack more times. This is especially dangerous with his huge Omni-strike as he can kill your whole army in one go, and the units that survive are cursed until his attack starts again with no downtime. Instead, use units with high damage per hit like Slapsticks. Slow is a great debuff against him, as his standing range is low. Cyberpunk Cat is good for this, as they outrange him. However, beware the contents of each stage he appears in, as they each feature a different niche and thus must be worked around.
*In each stage, there is strength magnification, the value of health and attack power varies because of this.
His Japanese name, Fugu Futo-kun, is a pun combining fugu, a Japanese dish composed of pufferfish meat, futoku, meaning "thick", and -kun, an informal honorific primarily used with boys' names and between peers and friends.