Like the other Cyclone bosses, Zyclone has an extremely fast attack rate, massive health and unbeatable DPS. However, it is also a Zombie enemy, which means that it can respawn after being killed. Unlike some other Zombies, however, it can revive an infinite amount of times! Like Metal Cyclone, Divine Cyclone, Primeval Cyclone, Super Cosmic Cyclone, Mesocosmocyclone and Li'l Zyclone it is not considered a Floating enemy, so anti-Floating abilities won't help against it. Unlike most other Zombies, it does not have the burrow ability and cannot sneak behind cats unless it is killed. This is probably due to the fact that it wouldn't work as a boss if it could be avoided entirely.
It is suggested to use ranged attackers and meatshields, just like against the other Cyclones. However, since this Cyclone can respawn, it is advised to either bring Zombie Killers or to have cats that can slip behind its dead body like Awakened Bahamut.